Sick for the last 5 months.

It is now September 1. I have been sick for 5 months.

The worst neurological symptoms of M.E. (myalgic encephalomyelitis) have subsided in the past couple weeks (though this disease is unpredictable and they could come back at any time). I finally started to work again on the programming project which was interrupted by the sickness and the WIPP catastrophe, though I have to pace myself and I am much slower than I used to be. The cognitive aspects are getting better, but the physical aspects of the disease (pain & fatigue) are still there and are worse in some ways.

This has been the damndest thing, everything I have done to cope with this disease I have learned myself, through trial and error, but especially going to Pubmed and trying to figure out what the hell is going on based on the symptoms I was having. This is a distinct neurological disease, but the medical establishment insists on confounding it with an inflammatory syndrome called CFS, or chronic fatigue syndrome. They even call it ME/CFS. This intentional confusion on the part of insurance companies and psychiatrists has caused untold suffering for people with severe ME. I have had a taste, just a taste of these very bad symptoms, and it is torture. There are people who have been suffering this torture for decades with no treatment, nothing to relieve the misery whatsoever. This is in spite of medications avaliable that are already in use for other diseases which have potential to relieve this suffering.

I have no doubt that oxidative stress from internal radionuclides is the cause of this disease in my case, but it was triggered by the flu-like virus that hit me 5 months ago. Something funky happened to my fingers a couple days before I got sick, they got pruney like they had been submerged in water. I also got minor Raynaud’s-like changes on the cuticles and nails. This is not a normal thing for flu or ILI (influenza-like illness) viruses. Perhaps I ws infected with two viruses. Usually ME is associated with enteroviruses or herpes viruses, which have a Th2 profile, and suppress Th1 cellular immunity. This suppression is augmented by the oxidative stress from radiation. When cellular immunity is deficient, the body cannot clear the viruses out.

Or it could be that the violent illness brought out the HHV-6 virus that hides in the brain, and that everyone has. According to the HHV-6 Foundation,

Like the other herpesviruses—Epstein Barr virus, varicella zoster virus, etc—HHV-6 establishes life-long latency and can become reactivated later in life. This reactivation has been associated with many clinical manifestations that can be seen in the “Associated Conditions” section of this site. Reactivation can occur in locations throughout the body, including the brain, lungs, heart, kidney and gastrointestinal tract. In some cases, HHV-6 reactivation in the brain tissue can cause cognitive dysfunction, permanent disability and death.

A growing number of studies also suggest that HHV-6 may play a role in a subset of patients with chronic neurological conditions such as multiple sclerosis, mesial temporal lobe epilepsy, status epilepticus and chronic fatigue syndrome.

I had incredible skin and joint inflammation since WIPP. And I had a pituitary tumor for over two years that shut down cortisol production. Dr. Martin Pall has said that inflammation and low cortisol are major risk factors for ME.

I am taking it one day at a time. Just barely hanging on.

“My bone cleaveth to my skin and to my flesh, and I am escaped with the skin of my teeth.” – Job 19:20

Hot rain moving through US and Canada with levels similar to 2011.

The Fukushima activity increase that started in early July continues to increase. High radiation levels have been measured in rain in Wisconsin, Illinois, Michigan, Ohio, and Ontario for the last couple of days. Vegetation is being affected and damaged by this rain.

It originated in a storm system that moved into the Pacific Northwest around August 12. It moved across the continent, just north of the US/Canada border, before dipping back south into the US in the Great Lakes area.

Julie Wert made this measurement:

This storm system was in the Great Lakes area last night. It is moving towards the east coast, and will affect Ontario, New York, Pennsylvania, Maryland, and Virginia by tonight.

Majia has noted extensive activity from the Fukushima webcams on her blog.

UPDATE: Diane Steele took these photos of her squash and bean plants after the hot rainstorm moved through her home in Minnesota. This damage was not there prior to this rain.

Hot rain in eastern Ontario, Aug. 21:

Aug 21st 2014 Hot rain

The Pacific Genocide.

BeautifulGirlByDana has streamed a video on Youtube, in which he and an associate traveled 200 km along the British Columbia coast, and photographed tidal pools at low tide. They found very few species of sea life still left alive in the pools. Most of the birds and insects were gone, also.

HORROR " Pacific Ocean Now Dead From Fukushima Radiation "

This is due to an ecological crisis triggered by Fukushima radiation in the Pacific. The radionuclides have caused a breakdown of the tightly woven and interconnected web of sea life. This life was not all killed by radiation itself… but also from other factors which were set in motion by the plume of radioactively contaminated seawater. The sea surface temperature is at record high levels due to decay heat from the radiation. Dead sea organisms alter the pH levels of the water. Oxygen is depleted, cyanobacteria and fungi thrive, cyanotoxins and mycotoxins are released, parasites thrive as immune functions degrade. Many species simply starve to death.

This is NOT due to global warming, chemtrails, HAARP, chupacabras, or reptilians. It is caused by Fukushima corium leaking into the Pacific.

And this is just the beginning. The plume of contaminated water has just recently arrived. The radioactivity concentrations will continue to increase until 2017.

But this plume is simply from the initial releases in 2011. The radioactivity continues to be released into the Pacific, and will do so for thousands of years.

Pacific radiation plume, August 2014.

Pacific radiation plume, March 2017.

I have made a list of articles relating to the Pacific genocide from Enenews. This goes back to April 1, when I got sick. I’m way behind on all this.

Copying one story title and pasting it into Google should bring the article up.

TV: “Mysterious die off of young salmon” in Pacific Northwest — “Healthy… and then they die” heading out to sea — “Far less plankton than normal… There are too many questions” — Researchers now testing for plankton and Fukushima contamination off West Coast (VIDEO)
Published: August 6th, 2014

Alaska: “Scientists alarmed by new mystery disease” — Pacific Northwest: “Alarming changes” — “Couldn’t believe my eyes” — “Scientists really stumped… It’s kind of an alien thing” — “Gotten much, much worse… a horror show… could wreak havoc on entire ecosystems from Mexico to Alaska” (VIDEO)
Published: August 6th, 2014

TV: Huge increase in dead and sick sea mammals on California coast — Unprecedented numbers, annual record broken in 7 months — Starving, drooling, brain damaged, suffering seizures — Sea lions ‘mysteriously’ vanishing on other side of Pacific — Experts: We don’t know what’s happening (VIDEO)
Published: August 3rd, 2014

TV: Millions of fish dead at Oregon coast — “Craziest thing I’ve ever seen” — “You can’t blame people for being alarmed” — Aquarium: “It kind of looks like the apocalypse… especially big numbers… but this is a sign that anchovies are doing good” (VIDEO)
Published: August 1st, 2014

Millions of fish found dead on California coast — 3 major fish kills in 2 weeks — Unidentified ‘goo’ floating nearby; Police clear out beach, call health officials to investigate (VIDEO)
Published: August 1st, 2014

Report: “Worst he’s ever seen” says Alaska boat captain — Fishermen “talking about Fukushima… convinced it has something to do with it” — Salmon “not showing up… many have lesions or worms and parasites” — Crabs “more easily damaged… a lot of dead catch” — Herring, cod, halibut, pollock catches “dropping off cliff”
Published: July 31st, 2014

Video: Fukushima debris “waist high” on Canadian island; “Catastrophic death” trapped in nets, it’s horrifying; 15-mile long lines of floating trash — Journalist: Radioactive tsunami debris found far from Fukushima plant — Global concern over spread of contamination
Published: July 29th, 2014

TV: Mounds of millions of jellyfish-like creatures wash up on Pacific beaches across multiple states — “They lined entire Oregon Coast” — Seen for first time in a great many years — Official: “They just covered the sea surface… as far as we could see” — Thought to mix with ones from Japan (VIDEO & PICS)
Published: July 29th, 2014

CBS: This is really disturbing, sea stars dying by the millions on West Coast — Like the Black Death, only faster and deadlier — ‘Mystery plague’ affecting 20+ species — TV: Disappears from Orange County coast over 2 week period — Expert: “Largest epidemic ever in ocean… Something has changed in marine environment to lead to this” (VIDEO)
Published: July 29th, 2014

Researchers: Radioactive materials detected off California, levels spike to 400% normal — Crew then discovers ‘island’ of tsunami debris — Never seen so much garbage in ocean before — TV: “Disturbing new images from Pacific… looks like islands of plastic” 1,000 miles from coast — 7 tons and 80 ft. long, can walk on it as if land (VIDEO & PHOTOS)
Published: July 28th, 2014

AP: Marine birds disappearing in Pacific Northwest — Significant ecological shift, crashes in many species — “Something’s happening on a big level, but what is it” — Herring problem may be far worse than revealed… result of contamination? Mexico suddenly bans bluefin tuna fishing, US may be next
Published: July 28th, 2014

Officials in U.S. report “very rare mutations” in Pacific sea life — “Never seen anything like this” — Photos show red crabs completely white, “shockingly bright blue… almost unnatural”, or with yellow legs — Environment “could play a role” — Also observed recently by Japan (VIDEO)
Published: July 22nd, 2014

Professor: Fukushima scaring ‘bejesus’ out of everybody in world… still flowing in ocean, radiation levels unknown — Clearly detectable in tuna at California coast… We focus a lot on bio-accumulation — Japan: Reactor leaks “may have gathered as a lump and drifted offshore, we need to continue monitoring it” (VIDEO)
Published: July 21st, 2014

TV: Fukushima radioactive releases into ocean can continue thousands of more years, says nuclear expert — Japan gov’t concerned with tracking radioactive waste in Pacific as it returns to Fukushima from U.S. West Coast after several decades (VIDEO)
Published: July 12th, 2014

Newly released data shows 4,000% more radioactive material in Fukushima groundwater than Tepco claimed — 39 billion Bq/m³ in sample from shoreline… after going through filtration process — Results not made public until almost a year later (VIDEO)
Published: July 8th, 2014

Gov’t Expert: Plutonium is certainly being discharged into Pacific Ocean from Fukushima plant; Flowing out of ruptured containments — TV: Reactor water turns into ‘yellowish, fizzing liquid’ from damaged fuel rods… “It actually vibrates” (PHOTO & VIDEO)
Published: July 1st, 2014

Japan Gov’t-funded Study: Fukushima has released up to 120 Quadrillion becquerels of radioactive cesium into North Pacific Ocean — Does not include amounts that fell on land — Exceeds Chernobyl total, which accounts for releases deposited on land AND ocean (MAP)
Published: June 30th, 2014

Newspaper: Increasing worry on West Coast over Fukushima radiation; “Really concerned” about affect on wildlife and most importantly our health; ‘Big black hole’ where data should be — Professor: “We do not know full extent… we’re just watching the West Coast unfold” — Official: Important we sample for plume — Fish oil being tested
Published: June 26th, 2014

TV: New concerns at Fukushima; Radioactive material “spilling into ocean” from layer 80 feet deep, officials suspect — Jiji: Record high radiation levels at 18 locations between reactors and Pacific; Crisis far from under control (VIDEO)
Published: June 25th, 2014

NHK: Fukushima responsible for “largest-ever” amount of radioactive pollution… “We did something terrible” — Scientist: Nuclear fuel “still melting down… there’s melting happening in the cores” (VIDEO)
Published: June 21st, 2014

S. California fishermen ‘skunked… haven’t seen a squid’, usually 10,000+ lbs/day — ‘Complete crashes’ at oyster hatcheries — Sardines, mackerel missing in areas — Pelican sites alarmingly deserted — Record # of sick sea lions — Ultra-rare whales appear after decades — Mammals, birds, fish in odd places
Published: June 17th, 2014

TV: “The largest disease outbreak that we know of ever in the oceans” now hitting West Coast — Potential for “global extinction” — “Affects over 20 species… causing catastrophic mortality” — Expert: One of history’s largest wildlife die-offs… signal in ecosystem that something’s not right (VIDEO)
Published: June 16th, 2014

Experts: Disease explosion in West Coast sea stars — “Extinction event” is pretty close — “Epidemic of historic magnitude… threatens to decimate entire population” of species in Oregon — Sudden 50-fold increase in recent weeks — Entire ecosystem could be disrupted — “We have no clue” (VIDEO)
Published: June 11th, 2014

“Fukushima, the world’s permanent headache” — Gundersen: It will be bleeding into Pacific for next 100 years — ABC: “Greatest nuclear contamination of the ocean in history… it can’t be quantified… it’s a global issue” (AUDIO)
Published: June 10th, 2014

Senior Scientist: Fukushima is not under control; It has ‘alarm bells’ going off on West Coast — Former Official: I’m humiliated Japan lies to world about how much contamination is entering Pacific; Nuclear material “polluting ocean more and more” (AUDIO)
Published: June 4th, 2014

AP: Drastic plunge in baby California pelicans — Zero born in multiple study areas — Expert: “The bottom dropped out”; From 1,000s to 10 or less, unknown why it’s occurring
Published: June 2nd, 2014

Official: Breach at Fukushima reactor blamed on saltwater corrosion — Over 75 tons of highly radioactive liquid flowing out everyday (PHOTOS & VIDEO)
Published: May 29th, 2014

Professor: Just 1% of usual number of baby California pelicans; “Nearly complete failure to breed”; Only 20 newborns in area where 10,000 expected — Expert: ‘Flabbergasted’ by what’s happening in Malibu, “I’ve never seen anything like that” (AUDIO)
Published: May 28th, 2014

TV: “Like a horror show” at Los Angeles-area beach — Unusual number of marine animals suddenly getting sick and dying — “I wonder if something’s in the water” killing them — They “hobble and fall over, it’s heartbreaking” (VIDEO)
Published: May 24th, 2014

CNN: Fukushima fallout ‘grossly underestimated’ says new Japan study — “Radioactive poison… contaminating the North Pacific Ocean” — Tepco: ‘Impossible’ to know how much really got out (VIDEO)
Published: May 22nd, 2014

Gov’t Report: Elevated radiation on California coast to last “several decades” — Local marine life “will accumulate” Fukushima radioactive material — Plutonium a potential concern — “On-going monitoring clearly warranted” yet ‘surprisingly little’ underway (VIDEO)
Published: May 21st, 2014

Hundreds of tons of radioactive water now being intentionally dumped into Pacific at Fukushima plant — Tepco: “We’d like to express our sincere appreciation” — Nuclear water stored since last year to be dumped next week — Official: Tepco “utterly inept” at taking accurate radiation readings (VIDEO)
Published: May 21st, 2014

Gov’t Report: Fukushima released up to 181 Quadrillion Bq of cesium, Chernobyl was 105 Quadrillion — Radioactive material to flow from Japan “for years to come” — Fukushima radionuclides have now spread “throughout N. Pacific”
Published: May 20th, 2014

Japan Times: “Radiation has spiked to all-time highs” in ocean off Fukushima plant — Jiji: “Record-high radiation levels have been observed” Tepco says — Officials: “Cause of seawater spike is unknown”
Published: May 18th, 2014

‘Mystery disease’ on Pacific coast of Alaska — Livers ‘crumble’… Hearts enlarged, pale… Yellow lymph nodes… Blood-filled lungs (PHOTOS) — Professor: Worrying there’s no answers, big public health concern — Testing carcasses for Fukushima radioactivity (AUDIO)
Published: May 16th, 2014

CNN: “Problem from hell at Fukushima” — Tons of ‘highly radioactive’ liquid pouring out of Reactor 2 each day — Mysterious explosive bang “deep inside” — 3 areas at bottom may be ruptured — Caroline Kennedy at Plant: US will help with the leaks; 21 y/o son also on Tepco’s 3 hour tour (VIDEO)
Published: May 14th, 2014

‘Bizarre creature’ turned 50 miles of California coast into graveyard in summer 2011 — Gov’t Biologist: Die-off like this never seen here — “Abalone massacre… carcasses of urchins, starfish, other mollusks” — Experts find “alterations in 30 genes, some unknown to science” — “Suddenly proliferating… killing wildlife” (PHOTO)
Published: May 12th, 2014

Professor: Concern that Fukushima is impacting Alaska; “Unusual animals showing up dead… Seals w/ unknown disease… 1st ever cases of avian cholera” — Govt investigating ‘rare whale beachings’ in Alaska — Japan Paper: Mysterious sea creatures found one after another (PHOTOS)
Published: May 10th, 2014

Over 50 dead seals, sea lions, whales, walrus recently stranded in Alaska — Dozens of seals suffering from baldness, skin sores — Experts: “Marine transported Fukushima radionuclides… may represent a new stressor to ecosystem”
Published: May 6th, 2014

Alarm as record numbers of seals & sea lions ‘starving to death’ along California coast — “It’s just spiked… calls started coming nonstop” — “So many unhealthy… washing ashore” — “Extremely complex issue… multitude of factors in play” — “Definitely a mystery, we’re hoping it’s not the new norm”
Published: May 4th, 2014

Gov’t Investigator: Acute hemorrhaging found in dead owls along west coast — Mortality event began 8 months after Fukushima explosions — “In very poor condition… badly emaciated” when arriving in Pacific Northwest from Arctic
Published: May 3rd, 2014

‘Marine Mystery’ in California: “Toxic outbreak threatening marine life” — Birds falling from sky, sea lions convulsing — “Worst they’ve ever seen” — Toxin hits record level, almost 1,000% above gov’t limit — Heart lesions, severe shrinking in part of brain, nervous system failure (VIDEO)
Published: May 3rd, 2014

State Senator: Fukushima is “damaging the oceans and devastating the environment”; An enormous crisis that has no foreseeable resolution — U.S. Senator: People are concerned about Fukushima radiation entering our waters, I want to know agencies plan to respond to “issues that may arise”
Published: May 1st, 2014

No plan to stop Fukushima from contaminating Pacific? Tepco adviser ‘doubts’ ice wall can stop groundwater from flooding plant — We’re concerned it may affect ‘environmental protection’ and cause ‘unintended consequences’ (VIDEO)
Published: May 1st, 2014

SF Chronicle: “Unbelievable hordes” of fish near California coast; Most birds, sea lions, dolphins, whales anywhere — Expert: ‘Off the charts’ pelican population “highly unusual… could reflect breeding failures elsewhere”; “Abnormal ocean conditions” to blame?
Published: May 1st, 2014

“Prestigious group of international scientists” interested in risk to West Coast from Fukushima radioactive plume — “Major concern for public health of coastal communities” — Bioaccumulation potential in region must be understood
Published: April 30th, 2014

NHK: Officials admit it may be impossible to stop leaking at Fukushima reactors — Will be investigating ‘bottom of containment vessels’ for holes — Gov’t asking engineers from outside Japan for help with melted fuel (VIDEOS)
Published: April 30th, 2014

USA Today: Radiation tripled in some albacore tuna off West Coast after Fukushima — Bioaccumulating in bones, not only flesh — “Additional exposures to plume could further increase radiation levels” — NOAA-funded study to expand after ‘significant’ findings (AUDIO)
Published: April 29th, 2014

PBS Reporter Miles O’Brien: “No one likes to see ocean filled with cesium and strontium and so forth” — It’s arriving on West Coast of U.S. as we speak — “Nobody likes the idea of eating cesium from Fukushima” — “Tainted water dumped into Pacific as we speak” (AUDIO)
Published: April 25th, 2014

Journal: “Fukushima has an Ongoing Melt-Out” — “Is this not the worst possible outcome?” — “Nuclear fuel mixing with groundwater and leaking into sea” — “Disaster never seen in human history and imagined only in movies” — Tokyo Paper: “A situation in which massive accidents occur daily”
Published: April 24th, 2014

Japan Times: “Irreparable damage” from Fukushima — Plant’s boss admits water problems “out of control” — Catastrophe “remains ongoing… shows no signs of resolution”
Published: April 20th, 2014

CBS San Francisco: Record number of sick seals & sea lions — Doctor: A lot with “large pockets of green and yellow puss all over their body” (PHOTO & VIDEOS)
Published: April 20th, 2014

NBC: Record level of sick or injured California seals and sea lions turning up — “The numbers are extraordinary” — “Scientists worried… The worst kind of perfect storm” — Pups should be weighing 2 or 3 times as much, “severely malnourished” (VIDEO)
Published: April 18th, 2014

NHK Special: Extremely toxic water 4,000,000 times gov’t limit in trenches between Fukushima reactors and ocean — Experts: “Source of contamination for Pacific” — “Levels too high for them to get more precise look at situation” — Reporter: Plutonium leaked out after fuel rods damaged (VIDEO)
Published: April 18th, 2014

L.A. News Outlet: Fukushima plume worries to sink fishing industry? Area newspapers “warning readers to avoid eating locally-caught fish” — Homeland Security Center director: Banana has 100 times more radiation (VIDEO)
Published: April 17th, 2014

Vancouver Sun: Scientists concerned dolphin species on west coast to be negatively impacted by Fukushima nuclear waste — Radiation levels to be increasing for years to come along coast — Canadian gov’t sampling for Iodine-129 in Pacific
Published: April 15th, 2014

Senior Scientist: Cancer increase expected on West Coast from Fukushima exposures; Radioactive particles can bio-accumulate and form hotspots while crossing Pacific — KCRW: Concern California wildlife to be impacted; Sea life can biomagnify nuclear waste, leading to higher levels of radiation (AUDIO)
Published: April 14th, 2014

Radioactive Spike in Ocean off Fukushima: Highest Cs-137 levels at location since 2011 — 22,000 Bq/m³ in Pacific outside port — Japan notifies IAEA of ‘elevated’ readings (MAP)
Published: April 14th, 2014

New radioactive leak reported at Fukushima on Sunday — Previous leak admitted to be “far more toxic” than public told — Over 80 trillion becquerels flowed into Pacific, unspecified amount of “nuclear fuel material” — Already rated an INES ‘Level 3′ incident using the much lower incorrect figures
Published: April 13th, 2014

Nuclear Engineer: Radiation levels “much higher” in areas of Fukushima plume headed to west coast than models show — Radio: Concern “other isotopes” besides cesium to cross Pacific (AUDIO)
Published: April 11th, 2014

Marine Chemist: Highly contaminated waste flowing in aquifer below Fukushima — Mag: Groundwater can ‘erupt’ from seafloor offshore — Gov’t expert warned about radioactive substances ‘springing up’ in Pacific (PHOTOS)
Published: April 6th, 2014

Professors: Seafood off N. American coast predicted to exceed gov’t radioactivity limit — “High priority looming threat” to global ocean from Fukushima releases — Radiation levels ‘well above’ 1,000 Bq/kg according to model
Published: April 6th, 2014

Reports: Sea stars decimated on West Coast — SoCal ravaged as mystery disease spreads south; Saw hundreds last year, now none… got hit really hard — Mortality event like this never before documented — “Uncharted waters… likes of which we haven’t seen” — Turning to ‘bacterial goop’ (RADIO)
Published: April 5th, 2014

Award-winning project finds seafood sold in Canada with high radiation levels — Many samples well over contamination limit — “Incredible discovery; Something unexpected may be lurking in Canadian waters” — Believes dangerous Fukushima pollution carried across ocean — “I hope people will open their eyes”
Published: April 2nd, 2014

Foreign reporters find radiation levels over 100 times legal limit off Fukushima — Captain: Radioactive releases “may last until end of the Earth” — “Deep sense of dread set in… Stop, don’t go any closer!” — “World deserves honest assessment of the disaster” — “A worst-case scenario come to life” (VIDEO)
Published: April 2nd, 2014

Radio: “Surprisingly, high concentrations [of Fukushima cesium] found in Vancouver area” since ocean currents slow down — Levels are increasing — “Might be hotspots where radiation concentrates” — “Chances are high for marine life to absorb it… concern about mussels… clams, oysters” (AUDIO)
Published: April 1st, 2014

TV: Gov’t not measuring worst of Fukushima radiation — Over 100 Million gallons of radioactive water bleeding into ocean from plant — We’re beginning to see radiation in west coast water — Very concerned about eating fish from Pacific (VIDEO)
Published: April 1st, 2014

Latest Fukushima plume is not going away.

On July 18 I posted about the latest Fukushima plume, and how it may have been the worst since last September. Well, it is still raging and getting worse. Majia has good info and links about recent webcam activity. I said earlier that, having come down with ME, I’m not a canary anymore, and I can’t tell about radiation, with all the noise coming from my body due to this radiation-caused disease… but I had an outbreak of dermatitis this past weekend. I don’t usually get this skin disorder, but skin symptoms (psoriasis) have always indicated radiation plumes in the past. My immune system has changed, and so now it’s a different skin disorder. Half of my eyebrow hairs fell out, too.

EnviroReporter has a good summary of the latest beta radiation figures from the EPA monitors:

U.S. Radiation Report 6 August 2014

Elevated TSH levels among California newborns after Fukushima.

Well, something is going on. Yesterday I went to two stores, and I actually went for a walk halfway around the shopping mall. I have not walked that much in two months. In fact, I hardly have been going out of the house at all more than once a week. I did pay for it today, with increased neurological symptoms.

But I decided the hell with it, I was going to do an analysis. I haven’t done any programming for four months, ever since the flu/M.E. nightmare started.

Let me tell you how important computer programming is to me. I started programming in 1971, when me and my friend Joel would sneak into the computer lab after hours in high school. They had a phone modem thingy. My first program was a computer baseball program written in BASIC. I picked up the language as I went along.

When I went to college, I learned FORTRAN by using punchcards. This ain’t easy. Punchcards are hardcore. They teach you to not make mistakes. This isn’t the touchy-feely BS they teach nowadays. I am a scientific programmer. I need speed and control.

I bought the original IBM PC in 1982. One of my first programs was an astrology program. I programmed the movement of the planets, any day for 1,000 years. I had to learn Bessel functions and that kind of stuff.

I have developed large database-driven systems for corporations. I have been invited to organize two major conference sessions in academic systems engineering. I have been wined and dined by corporate executives for a printing press scheduling program I wrote. (There is a story behind this. It goes into the inexplicable-things-that-have-happened-to-Bobby1 category. Not right now.)

So I have been always programming, for work, or for my own enjoyment or interests. Till I got sick.

Today, after four months, I was able to do an analysis. It just involved programming in VBA, nothing special. Though the data set was so large I had to expand MegaODA, so I had to find the program, expand its limits to 3 million observations, and recompile it in FORTRAN. I forgot if my computer had SSE4.1 on it, so I had to find and run CPU-Z to verify this.

This is like a marathon runner who suffers a devastating injury, and four months later, is able to take a few halting steps, while everyone applauds. Except nobody is applauding. I have a warm feeling in my heart, that’s all.

THANK YOU JESUS!

Oh, and by the way, this is the most significant result yet on American patients’ health in relation to Fukushima. It is more significant than my 2011 mortality study.

The data came from the Genetic Disease Screening Program at the California Department of Public Health. These are TSH (thyroid stimulating hormone) levels of California newborns for the period 2009-2012. Mangano, Sherman, and Busby used this same dataset for their paper on congenital hypothyroidism which was incomprehensibly botched. Dr. Yarnold and I made comments on this paper here.

While Mangano et al. created arbitrary classifications of hypothyroidism, which are not used in practice, these results reflect TSH levels before and after Fuku. TSH is implicated in many diseases, not just hypothyroidism. It affects the entire hypothalamus-pituitary-thyroid axis. For one thing, increased TSH levels cause the newborn to absorb more iodine-131 than average TSH newborns would.

This is also important because it involves the effect of all species of radioisotopes, I-131, Cs-137, Pu-239, etc. etc. We don’t know if only I-131 affects newborns, in fact Dr. Bandazhevsky has shown that Cs-137 affects thyroids too.

The data have been split up into three seasons:

1. January 1 – March 16
2. March 17 – June 30
3. July 1 – December 31

It involves virtually the entire population of California newborns for the years 2009-2012.

AFTERFUK is an indicator variable, which equals 1 if the birth was after Fukushima, and 0 otherwise. “IF 4.5 < TSH THEN AFTERFUK = 1" means than if TSH is greater than 4.5 (actually 4.99 in the original data), then the newborn is classified as being born after Fukushima. ODA uses maximum-accuracy classification - no model of this form achieves higher classification accuracy. No distributional assumptions are involved.

All three seasons, and the combined data also, show increased TSH levels after Fukushima, and all are statistically significant by two-tailed UniODA at the p<.01 level.

The ESS levels vary from 3.90% to 8.02%. The effect is weak, but I am not a thyroid doctor. Since over two million newborns are involved, even a small effect has consequences for many newborns. I would think that something that would affect even 100 newborns is a big huge deal.

Analysis for January 1 – March 16.

Analysis for March 17 – June 30.

Analysis for July 1 – December 31.

Analysis for the combined seasons.

How ME and radiation sickness has altered my mechanism of thinking.

Yablokov et al. in their Chernobyl book demonstrated how radiation exposure affected the brains of liquidators and others at Chernobyl. The brain and central nervous system are some of prominent organs affected by radiation.

Profound cognitive changes have occurred since I came down with ME (myalgic encephalomyelitis) in April. It has affected the way I think, it has affected this blog, it has destroyed my career.

The first image below is a lattice. It reflects the way I used to think, in my previous 59 years. In developing large scientific computer programs, I would sit in a state of concentration for 7 hours at a time. “347 is related to 13, which is related to 3, which is related to 1245″ etc. I was able to visualize the entire thing in my head at once, and move up and down, changing something at the bottom, then moving to the middle or the top, and conceptualize how the small changes affected the entire system. This is also the way I digested information by reading, and how I was able to present it in writing. This whole blog deals with unifying disparate pieces of information on Fukushima and other issues, and combining them into an argument. This is why there is a unique perspective here, as I discover new things by seeing patterns.

Nonlinear lattice thinking.

Linear thinking.

Lattice thinking has gone away. This is difficult to adjust to. It is impossible to multitask in the slightest.

The other image describes linear thinking. “A leads to B, B leads to C, C leads to D”, etc. It’s a chain, not a lattice. I have never been good at this kind of thinking.

But it seems that, while I am now incapable of lattice thinking, the alterations in neurotransmitter functions of serotonin, glutamate, and GABA have IMPROVED linear thinking.

The slightest distraction or exertion will cause me to forget what I was just thinking a second before. Or it will simply go away, POOF. With linear thinking, that means I forget what B is. What I do is simply go back to A and start over. It doesn’t affect this type of thinking like it does the lattice. The only thing I have to do is remember A.

In fact, since I no longer have to remember the entire lattice, this condition has streamlined things, making it easier.

I made a post on Facebook extolling the virtues of fat, for my own health, and ME patients in general.

FAT IS GOOD (for me at least)…

I should go back to the redneck diet I had years ago. I want to have grease dripping out of my mouth. I want pulled pork in my teeth.

Fat increases lymphotoxin, which increases IL-22, which provides immunity to bacteria, and repairs gut tissues, and alters the balance of gut microbiota.

This was without reading any testimonials whatever from ME (ME/CFS) sufferers. It is a product of the thought process behind this blog post I recently published.

1. I had read from UNSCEAR and the National CFIDS Foundation that radiation exposure impairs STAT-1 functions in the JAK/STAT pathway.

2. When I suddenly came down with ME, my plaque and guttate psoriasis suddenly disappeared. This NEVER happens like this to anyone. The inverse psoriasis remained, but that really isn’t psoriasis of the same kind, it’s due to skin damage from uranium and fluoride, some from Fuku, but mostly from Honeywell.

3. I knew from my previous research in psoriasis that there are two mechanisms for psoriasis, one based on IL-17, the other based on IFN-γ and IL-22. It was obvious that the inverse was based on IL-17, and the plaque and guttate were based on IFN-γ and IL-22.

4. Since STAT-1 contains the genes that produce IFN-γ, and this cytokine had suddenly dramatically decreased, I started a chain of reasoning, A -> B -> C etc.

The lack of IFN-γ causes a lack of SMAD7. The lack of SMAD7 causes an increase in TGF-β. The increase in TGF-β causes Th22 cells to not be differentiated. The lack of Th22 cells causes a lack of IL-22.

See, it explains why the psoriasis suddenly disappeared. It’s all about STAT-1 impairment.

Also, IFN-γ is expressed in group 1 innate lymphoid cells (ILC1). ILC’s are located in Peyer’s patches of the intestines, and other lymphoid nodules. ILC3, or group3 cells, express IL-22. The damage to ILC1 causes damage to ILC3. This causes tissue damage to the gut, and bacterial translocation from the gut to other parts of the body.

I was able to predict that eating fat would repair ILC3, and cause improvement in symptoms. I mentioned this is an ME group, and found that others already do this. In fact, ketogenic diets are popular in treatment of this condition. I had not known this.

So I was able to reason, starting from a particular kind of radiation damage, and presented a hypothesis, which was confirmed. This is what science is all about.

I know that I am on the right track, I know that ME is really radiation sickness, and I know that ME is not an autoimmune disease, but an immune deficiency disease, characterized by a loss of cellular immunity. But I’ll be damned if I can organize something which would demonstrate or prove this. That requires lattice thinking.

But maybe I am still good for something, maybe I can work again, but I don’t know just at what yet.

Latest Fukushima plume. Worst since Sept. 2013?

Lots of alarm bells ringing. Fukushima Diary has a story about a spike in radiation after a small earthquake. This is corroborated by many other monitors nearby Fukushima. Majia has been reporting on increased webcam activity. I saw on Facebook that radiation levels in Taiwan have risen, and there are high readings in the Midwest US. And there is this reading from a rain sample in Alberta, Canada:

Radioactive Rain – July 17 2014 – 11:20pm

4.98 μSv is pretty bad. Probably 25-40 times normal background. There were previous spikes this year in January and May, but this might be worse. The Aug-Sept 2013 release was really bad. It remains to be seen if this new one is worse. I haven’t looked at sludge data yet.

I can’t tell anymore from my own health. The ME swamps everything with its own signals. Autoimmune disease was so easy then.. relatively.

Origin of M.E. disease process in the immune system.

The sudden onset of M.E. (myalgic encephalomyelitis, ME/CFS) 3 months ago occurred when I when I was experiencing a flare of psoriatic arthritis, an autoimmune disease. The virus infection caused an huge amount of inflammation. Everything suddenly changed virtually overnight… so I have a personal insight into the ME disease process that doctors and other patients may not have.

Internal radiation exposure causes damage to the JAK/STAT pathway.

The JAK-STAT signaling pathway transmits information from chemical signals outside the cell, through the cell membrane, and into gene promoters on the DNA in the cell nucleus, which causes DNA transcription and activity in the cell. The JAK-STAT system is a major signaling alternative to the second messenger system.

The JAK-STAT system consists of three main components: (1) a receptor (2) Janus kinase (JAK) and (3) Signal Transducer and Activator of Transcription (STAT).[1]

Many JAK-STAT pathways are expressed in white blood cells, and are therefore involved in regulation of the immune system.

The receptor is activated by a signal from interferon, interleukin, growth factors, or other chemical messengers. This activates the kinase function of JAK, which autophosphorylates itself (phosphate groups act as “on” and “off” switches on proteins). The STAT protein then binds to the phosphorylated receptor, where STAT is phosphorylated by JAK.The phosphorylated STAT protein binds to another phosphorylated STAT protein (dimerizes) and translocates into the cell nucleus. In the nucleus, it binds to DNA and promotes transcription of genes responsive to STAT… (link)

The STAT protein (Signal Transducer and Activator of Transcription, or Signal Transduction And transcription) regulates many aspects of growth, survival and differentiation in cells. The transcription factors of this family are activated by Janus kinase (or ‘Just Another Kinase’, JAK) and dysregulation of this pathway is frequently observed in primary tumours and leads to increased angiogenesis, enhanced survival of tumours and immunosuppression. (link)

Specifically, radiation impairs the activity of STAT-1 protein, which is required for IFN-γ signalling. (link) IFN-γ is the hallmark Th1 cytokine, which is involved with cellular immunity.

We have recently characterized different mutations responsible for partial STAT1 functional deficiency. STAT1 is an essential protein for the signal transduction induced by IFNγ, under its homodimeric form (STAT1/STAT1, known as GAF) as well as its heterotrimeric form (STAT1/STAT2/p48, of ISGF3)… As a result, these observations prove that IFNγ-mediated anti-mycobacterial immunity depends on STAT1 and GAF. The characterization of patients with a STAT1 complete deficit and showing severe viral infections demonstrates that type I IFNs-mediated antiviral immunity is STAT1-dependent and ISGF3-dependent, at least for Herpes viruses. (link)

ME/CFS is usually linked to herpes viruses, Epstein-Barr viruses, or enteroviruses. Degradation of the STAT-1 pathway reduces immunity to these viruses. Herpes viruses hide in the immune system. They can become reactivated at any time. Everyone has these viruses latent in their systems since childhood. They are just waiting for a trigger to come back.

Smad7 is a protein, the expression of which is induced by STAT-1 and IFN-γ.

SMAD7 is a protein that, as its name describes, is a homolog of the Drosophila gene: “Mothers against decapentaplegic”. It belongs to the SMAD family of proteins, which belong to the TGFβ superfamily of ligands. Like many other TGFβ family members, SMAD7 is involved in cell signalling. It is a TGFβ type 1 receptor antagonist. It blocks TGFβ1 and activin associating with the receptor, blocking access to SMAD2. (link)

Here we present a basis for the integration of TGF-beta and IFN-gamma signals. IFN-gamma inhibits the TGF beta-induced phosphorylation of Smad3 and its attendant events, namely, the association of Smad3 with Smad4, the accumulation of Smad3 in the nucleus, and the activation of TGFbeta-responsive genes. Acting through Jak1 and Stat1, IFN-gamma induces the expression of Smad7, an antagonistic SMAD, which prevents the interaction of Smad3 with the TGF-beta receptor. (link)

So radiation damages the STAT-1 pathway, reducing IFN-γ, and reducing Smad7, which causes uncontrolled growth in TGF-β levels. This cytokine suppresses the immune system further, and causes the development of Treg cells, which regulate and suppress the immune system.

TGF-beta and CD4+CD25+ regulatory T cells (Treg) both play an important role in the control of immune responses and the maintenance of immune homeostasis. The mechanism of suppression induced by Treg and the factors which regulate Treg function and number, have only begun to be elucidated. TGF-beta seems to act as an effector cytokine involved in the immunosuppressive function of Treg in vitro and in vivo, although its origin and mechanism of action remains to be defined. In addition, TGF-beta signaling in peripheral Treg seems to be essential for the regulation of peripheral Treg numbers and for their immunosuppressive function in vivo. This review will focus on the role of TGF-beta for the generation and expansion of CD4+CD25+ Treg, as well as for their immunosuppressive function in vitro and in vivo. (link)

IL-22 (interleukin-22) is a cytokine that is produced by Th17 and Th22 cells. TGF-β counteracts IL-22 and reduces the differentiation of Th22 cells.

IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26),[4] a class of potent mediators of cellular inflammatory responses… IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 is rapidly produced by splenic LTi-like cells [6] and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems. (link)

IL-22 is an important part of immune protection against enteropathogens. Depletion of Th22 cells depletes IL-22.

Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria…

Interleukin-22 (IL-22) is central to host protection against bacterial infections at barrier sites. Both innate lymphoid cells (ILCs) and T cells produce IL-22. However, the specific contributions of CD4(+) T cells and their developmental origins are unclear. We found that the enteric pathogen Citrobacter rodentium induced sequential waves of IL-22-producing ILCs and CD4(+) T cells that were each critical to host defense during a primary infection. Whereas IL-22 production by ILCs was strictly IL-23 dependent, development of IL-22-producing CD4(+) T cells occurred via an IL-6-dependent mechanism that was augmented by, but not dependent on, IL-23 and was dependent on both transcription factors T-bet and AhR. Transfer of CD4(+) T cells differentiated with IL-6 in the absence of TGF-β (“Th22″ cells) conferred complete protection of infected IL-22-deficient mice whereas transferred Th17 cells did not. These findings establish Th22 cells as an important component of mucosal antimicrobial host defense. (link)

IL-22 suppresses bacterial translocation in the intestines, and promotes regeneration in the cells of the epithelial wall. It also activates STAT-3. IL-22 deficiency counteracts all this.

Intestinal mucus functions as a lubricant and a physiological barrier between luminal contents and mucosal surface (59). Mucin (Muc) 1, which is a heavily O-glycosylated membrane-bound mucin, represents one of the major components in the intestinal mucus (59)… Interestingly, a recent study proposes the ability of Muc1 to suppress the expansion of both Th17 cells and IL-17-producing ILCs presumably by blocking the translocation of bacterial products from intestinal lumen into intestinal lamina propria (62)… Interestingly, the ability of IL-22 to promote the production of functional Muc1 through activation of STAT3, but not STAT1, has been demonstrated using human colonic cancer cell lines (T84 and HT29) and primary colonic epithelial cells from mice (9,67)… IL-22 has been demonstrated to promote the epithelial cell regeneration with goblet cell restitution under intestinal inflammatory condition, but it may play no obvious role innormal colonic epithelial homeostasis in the healthy state (9,21). (link)

Cinnabarinic acid is a product of tryptophan metabolism, activates the aryl hydrocarbon receptor (AHR), and is an important source of IL-22.

The aryl hydrocarbon receptor (AHR) binds to environmental toxicants including synthetic halogenated aromatic hydrocarbons and is involved in a diverse array of biological processes. Recently, the AHR was shown to control host immunity by affecting the balance between inflammatory T cells that produce IL-17 (Th17) and IL-22 versus regulatory T cells (Treg) involved in tolerance. While environmental AHR ligands can mediate this effect, endogenous ligands are likely to be more relevant in host immune responses. We investigated downstream metabolites of tryptophan as potential AHR ligands because (1) tryptophan metabolites have been implicated in regulating the balance between Th17 and Treg cells and (2) many of the AHR ligands identified thus far are derivatives of tryptophan. We characterized the ability of tryptophan metabolites to bind and activate the AHR and to increase IL-22 production in human T cells. We report that the tryptophan metabolite, cinnabarinic acid (CA), is an AHR ligand that stimulates the differentiation of human and mouse T cells producing IL-22…

Although the AHR was initially proposed to affect Treg and Th17 development, a Th17-associated cytokine, IL-22, is even more specifically dependent upon AHR activation [13]. Ahr -/- mice retain the ability to generate some Th17 cells but are compromised in terms of IL-22 production [13,17]. Human T cell differentiation also exhibits distinct requirements for the AHR: activation of the AHR in stimulated human T cells was found to inhibit Th17 differentiation and to promote the differentiation of CD4+ T cells that produce IL-22 [18]…

Potential enzymatic modulators that can regulate the generation of CA from 3-HAA would predictably affect the resolution of inflammation. Such enzymes include ceruloplasmin [39], super-oxide dismutase [33], catalase [33], and the fungal virulence factor, laccase [39]…

We have shown previously that tryptophan catabolism can result in a loss of Th17 cells in the context of HIV disease through generation of 3-HAA [30]. We hypothesize that this loss, particularly within the gut mucosa, allows for ongoing inflammation due to continued microbial translocation. Conversion of 3-HAA into CA could reverse the effects of 3-HAA within immune cells, and thereby restore IL-22-producing cells in the context of increased IDO activity. This would allow for the resolution of the inflammatory signaling cascade by strengthening the mucosal barrier, thus stopping a vicious cycle that might otherwise drive disease progression [30]. Although IL-22 was initially linked to IL-17 as a pro-inflammatory cytokine, recent evidence suggests that it probably plays an independent immunoregulatory role in the context of non-hematopoietic cells, maintaining epithelial cell homeostasis in the mucosal tissues [50,57,58]. If so, the pathways that lead to the generation of CA may operate in tandem with the immunosuppressive mechanisms linked to tryptophan metabolism to generate a population of IL-22 producing cells that plays a specific role in tissue repair following inflammation [58]. (link)

So the initial insult of the disease that triggers ME causes massive inflammation, but the lack of IL-22 causes the damage from this inflammation to not be healed, which results in bacterial and viral translocation from the gut. Consequently, the patient is repeatedly re-infected with these pathogens. The lack of IFN-γ and IL-22 reduces innate and adaptive immunity to these pathogens. Tryptophan metabolism is also affected, and its normal function in healing of the gut is abrogated by excessive amounts of TGF-β.

This immune process begins a dysfunctional process that affects the entire body. But it begins with STAT-1 impairment. An effective treatment for M.E. would target the source. Everything else has to do with reducing symptoms.

The canary died.

Well, it has come. I am no longer a radiation canary. The ME (myalgic encephalomyelitis) I have developed after a very bad bout with influenza has its own ups and downs, and I can no disentangle the radiation ups and downs from it… and I am not sure that I even have radiation ups and downs anymore. I’m just screwed.

canary in a coal mine

An allusion to caged canaries (birds) that mining workers would carry down into the mine tunnels with them. If dangerous gases such as methane or carbon monoxide leaked into the mine, the gases would kill the canary before killing the miners, thus providing a warning to exit the tunnels immediately.

(idiomatic) Something whose sensitivity to adverse conditions makes it a useful early indicator of such conditions; something which warns of the coming of greater danger or trouble by a deterioration in its health or welfare. (link)

I have been researching, writing, keeping a diary of my symptoms, talking about radiation-induced fungus, plant damage, other Japanese, Chinese, and American nuclear power plant meltdowns, the Bravo bomb, Fukushima, Honeywell Works, WIPP. I’ve been yelling and screaming.

That’s all behind me now, the rubber has hit the road, the shit has hit the fan. I am FRANTICALLY trying to stay one step ahead of this stupid disease, which few seem to know anything about, and especially doctors. Basically I have figure out what it is, from my own symptoms, and infer the whole damned disease process on my own, with increasing physical and cognitive impairment going on the whole time. I have to prioritize getting a handle on the symptoms so I can keep thinking, and so be able to find a more lasting solution to it.

So everything is all biochemistry now. I’m sorry… this is a radiation blog, but ME and its cousin CFS (chronic fatigue syndrome) are really radiation sickness anyway. So it is somewhat on topic. Maybe I will be able to help the rapidly expanding number of people who will come down with this.

I’ve done all I can. I have to try to save my own ass now. Thanks everyone.

Fukushima AIDS, part 4: ME/CFS.

Fukushima AIDS, part 1 here, part 2 here, part 3 here.

I spent the day looking for a treatment for the encephalomyelitis I developed after a severe viral infection. It appears that TGF-beta (the immune system cytokine, transforming growth factor beta) levels suddenly shot up a couple weeks into the illness, back in April. TGF-beta antagonizes IL-22 (interleukin-22), which is one of the pathways for psoriasis. It also causes an autoimmune reaction to the optic nerve. This is what happened. I developed uveitis on the back of the eyeball, where it joins the optic nerve, and the psoriasis suddenly went away. IL-22 also protects the intestines against inflammation, and when it went away, bacteria and viruses suddenly started moving through the blood-brain barrier. I had a “Th2 shift” from autoimmunity to allergy, and an immune reaction to serotonin developed… I am showing demyelinating symptoms like nystagmus and Bell’s palsy. Antibodies to the 5HT receptor myelin are being created. The myelin acts as an insulator for nerve impulses in axons, and it is being degraded, so this is affecting electrical transmission in the nervous system. Multiple sclerosis is a demyelinating disease, and there are some similarities to this.

The immune reaction to serotonin basically means that I have become allergic to my own nervous system.

I was having an extraordinary psoriasis flare when I came down with the flu. Psoriasis sufferers say the one good thing about their disease is that they never get sick. Well I had psoriasis real bad and I got real sick. The result was an extreme amount of inflammation. Massive amounts of cells were killed. So there were dead cells all over the place, full of bacteria, viruses, and radionuclides like plutonium. My immune system suddenly shifted to clear these dead cells out (apoptotic cell clearance). (link) Macrophages came to eat up these dead cells. But the cell clearance facility was impaired. The dead cells started leaking out.

It has been known for 25 years that TGF-beta levels shoot way up with radiation exposure. TGF-beta also causes hair loss… when you hear that radiation causes hair to fall out, it is because TGF-beta levels are elevated in the hair follicles.

This is really ME/CFS, or actually myalgic encephalomyelitis. (link) Both the serotonin antibodies and the bacterial translocation from the intestines are symptoms of this disease. (link)

Myalgic encephalomyelitis was officially listed as a neurolgical disease by the WHO in 1969. In 1988, the FDA changed the name of it to “chronic fatigue syndrome”. This was in the wake of Chernobyl. CFS became a “wastebasket diagnosis” when a doctor that couldn’t find out the reason for the fatigue would diagnose it as CFS, even if it was really due to heart disease or for some other reason. The upshot was that when researchers attempted to find biomarkers for the disease, the ME people were mixed together with the CFS people, and no consistent results could be found. This was by design. The Russians knew from Mayak and Chernobyl that encephalomyelitis was a consequence of chronic radiation sickness. There is almost no money allocated by the government for ME/CFS research.

The pituitary tumor medicine which I was taking, which is an agonist for the serotonin receptors, caused a reaction, and I had to stop taking it. If the tumor gets huge again, and I have this disease, I am in uncharted territory. I have searched Pubmed and there are no case reports for such a thing. There is nothing for a doctor to base his opinion on. I know it can’t be good. Anyway ME/CFS has no cure or effective treatment by itself, either.

So the idea is to reduce TGF-beta… alpha lipoic acid is an antioxidant that seems to help. Pomegranate and oak ellagitannins also help, I have used these before for arthritis. Certainly reactive oxygen species play a large role in this, which are countered by antioxidants.

Phenibut helps a lot, but only for symptomatic relief. It is similar to baclofen and Lyrica, a GABA-B agonist. Phenibut reduces the release of 5-HT into the brain, and consequently reduces the immune reaction to it. It doesn’t deal with the cause of this, but it makes life manageable. It is not going to stop deterioration of the nervous system.

This has been an ordeal. When it gets bad, the brain fog, tinnitus, pressure & headaches are so bad that I can’t think. I have a difficult time with distractions, and even when there is absolute peace & quiet I find it hard to organize disparate bits of information, which is what this blog is all about. I am a programmer, and my whole career has been about mental focus and concentration. That is what has gone away. It is certainly scary, it is getting worse, and I know that 25% of those with true M.E. are bedridden and need care. It is easy to see how this could happen, and soon.

I will try to keep this blog going as long as I can, while I try to get a handle on this.